The evaluation of the flow in the vascular system is a key aspect in the diagnosis of many pathologies. There are still major limitations in the imaging modes provided by the commercial scanners. The team proposes and studies several approaches to perform high quality robust and precise flow imaging techniques.
Among all aspects of blood flow imaging, one very active field of research is the proper evaluation of vector flow. This is of key importance because the flow is by nature multidimensional and to investigate properly the vascular system, this multidimensionality must be evaluated. Unfortunately, most current systems only provide the velocity along one direction making the evaluation of complex flow patterns extremely complicated.
After studying transverse oscillations for tissue motion, a technique initially developed at DTU Copenhaguen by Prof. J.A. Jensen, the team has also worked on its to high frame rate vector Doppler imaging. This work has been performed through two PhD projects.
First Matteo Lenge, who's PhD was performed in collaboration with the group of Piero Tortoli, adapted the beamforming transverse oscillation technique for plane wave imaging and applied it in vivo on healthy volunteers.
Example flow velocity estimated in the CCA superimposed with B-mode
images. Image from Matteo Lenge's PhD thesis
Then Vincent Perrot, who's PhD was performed in collaboration with the group of Lasse Lovstakken, further developed the filtering based transverse oscillation technique for plane wave imaging of the carotid artery and applied it in vivo on both healthy subjects and patients.
Example flow velocity estimated and pWSR estimated along the wall superimposed with B-mode
images for the internal carotid artery with stenosis. Image from Vincent Perrot's PhD thesis.