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Publications of N. Nighoghossian
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[BRIS-10a] J.C. Brisset,
V. Desestret,
E. Devillard,
S. Marcellino,
F. Chauveau,
F. Lagarde,
S. Nataf,
J. Honnorat,
N. Nighoghossian,
Y. Berthezène,
and M. Wiart.
Quantitative effects of cell internalization of two types of ultrasmall superparamagnetic iron oxide nanoparticles at 4.7T and 7T.
Eur Radiol,
20(2):275-285,
2010.
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[BRIS-10b] J.C. Brisset,
M. Sigovan,
F. Chauveau,
A. Riou,
E. Devillard,
V. Desestret,
M. Touret,
S. Nataf,
J. Honnorat,
E. Canet-soulas,
N. Nighoghossian,
Y. Berthezène,
and M. Wiart.
Quantification of iron-labeled cells with positive contrast in mouse brains.
Molecular Imaging and Biology,
pp in press,
2010.
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[CHAU-10b] F. Chauveau,
T.H. Cho,
Y. Berthezène,
N. Nighoghossian,
and M. Wiart.
Imaging inflammation in stroke using magnetic resonance imaging.
Int J Clin Pharm Th,
(in press),
2010.
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[CHAU-10a] F. Chauveau,
S. Moucharrafie,
M. Wiart,
J.C. Brisset,
Y. Berthezène,
N. Nighoghossian,
and T.H. Cho.
In vivo MRI assessment of permanent middle cerebral artery occlusion by electrocoagulation: pitfalls of procedure.
Experimental and Translational Stroke Medicine,
2:4,
2010.
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[CHO-09b] T.H. Cho,
M. Hermier,
J.A. Alawneh,
T. Ritzenthaler,
V. Desestret,
L. Ostergaard,
L Derex,
J.C. Baron,
and N. Nighoghossian.
Total Mismatch. Negative Diffusion-Weighted Imaging but Extensive Perfusion Defect in Acute Stroke.
Stroke,
40(10):(3400-3402),
2009.
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[CHO-09a] T.H. Cho,
N. Nighoghossian,
N. Tahon,
C. Nemoz,
M. Hermier,
F. Salkine,
L. Derex,
P. Trouillas,
J.C. Froment,
and F. Turjman.
Brain stem diffusion-weighted imaging lesion score: a potential marker of outcome in acute basilar artery occlusion.
Am J Neuro Radiol,
30:194-198,
2009.
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[DERE-09] L. Derex and N. Nighoghossian.
Thrombolysis, stroke-unit admission and early rehabilitation in elderly patients.
Nat Rev Neurol,
5(9):(506-511),
2009.
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[DESE-09a] V. Desestret,
J.C. Brisset,
E. Devillard,
S. Moucharrafie,
S. Nataf,
J. Honnorat,
N. Nighoghossian,
Y. Berthezène,
and M. Wiart.
Early stage investigations of USPIO-induced signal changes after focal cerebral ischemia in mice.
Stroke,
40:1834-1841,
2009.
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[DERE-09b] I.C. Ralea,
G. Rioufol,
S. Cakmak,
L. Derex,
and N. Nighoghossian.
Acute stroke and heart attack management within a four-hour time window.
J Stroke Cerebrovasc Dis,
18(2):(167-70),
2009.
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[RITZ-09a] T. Ritzenthaler,
N. Nighoghossian,
J. Berthiller,
A.M. Schott,
T.H. Cho,
L. Derex,
J. Brun,
P. Trouillas,
and B. Claustrat.
Nocturnal urine melatonin and 6-sulphatoxymelatonin excretion at the acute stage of ischaemic stroke.
J Pineal Res,
40(5):(1834-41),
2009.
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[NIGH-08d] N. Nighoghossian and L. Derex.
Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update.
J Neurol Neurosur Ps,
79(10):(1093-9),
2008.
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[NIGH-08a] N. Nighoghossian,
M. Wiart,
and Y Berthezène.
Novel Applications of Magnetic Resonance Imaging to Image Tissue Inflammation after Stroke.
J Neuroimaging,
28(2):390-395,
2008.
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[RALE-08] I.C. Ralea,
N. Nighoghossian,
F. Tahon,
L. Derex,
S. Cakmak,
P. Trouillas,
and Turjman F..
Stenting of symptomatic basilar and vertebral artery stenosis in patients resistant to optimal medical prevention: the Lyon stroke unit experience.
Eur Neurol,
60(3):(27-31),
2008.
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[TILI-08] C. Tilikete,
S. Hannoun,
N. Nighoghossian,
and D. Sappey-Marinier.
Oculopalatal tremor and severe late-onset cerebellar ataxia.
Neurology,
71(4):301,
2008.
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[BOUSS-07b] L. Boussel,
P. Douek,
and N. Nighoghossian.
High resolution MRI of isolated intraluminal clot of the common carotid artery.
Neurology,
68(10):788,
2007.
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[CHO-07a] T.H. Cho,
N. Nighoghossian,
M. Wiart,
V. Desestret,
S. Cakmak,
Y. Berthezène,
L. Derex,
G. Louis-Tisserand,
P. Trouillas,
J. Honnorat,
J.C. Froment,
and M. Hermier.
USPIO-enhanced MRI of neuroinflammation at the sub-acute stage of ischemic stroke, preliminary data.
Cerebrovasc Dis,
24(6):544-546,
2007.
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[NIGH-07a] N. Nighoghossian,
M. Wiart,
S. Cakmak,
Y. Berthezène,
L. Derex,
T.H. Cho,
C. Nemoz,
F. Chappuis,
J.L. Tisserand,
J.B. Pialat,
P. Trouillas,
J.C. Froment,
and M. Hermier.
Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients.
Stroke,
38(2):303-307,
2007.
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[PIAL-07a] J.B. Pialat,
T.H. Cho,
O. Beuf,
S. Moucharrafie,
J.B. Langlois,
C. Nemoz,
M. Janier,
Y. Berthezène,
N. Nighoghossian,
and M. Wiart.
MRI monitoring of focal cerebral ischemia in peroxisome proliferator-activated receptor (PPAR)-deficient mice.
Nuclear Magnetic Resonance in Biomedicine,
20(3):335-342,
2007.
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[WIAR-07b] M. Wiart,
N. Davoust,
V. Desestret,
N. Nighoghossian,
and Y. Berthezène.
Response to Letter by Bendszus, Kleinschnitz and Stoll: Iron-enhanced MRI in ischemic stroke: intravascular trapping vs cellular imaging.
Stroke,
38:13,
2007.
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[WIAR-07e] M. Wiart,
N. Davoust,
J.B. Pialat,
Y. Berthezène,
and N. Nighoghossian.
Magnetic resonance imaging (MRI) of inflammation in stroke.
Conf Proc IEEE Eng Med Biol Soc,
2007:(4316-9),
2007.
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[WIAR-07a] M. Wiart,
N. Davoust,
J.B. Pialat,
V. Desestret,
S. Moucharrafie,
T.H. Cho,
M. Mutin,
J.B. Langlois,
O. Beuf,
J. Honnorat,
N. Nighoghossian,
and Y. Berthezène.
MRI monitoring of neuro-inflammation in mouse focal ischemia.
Stroke,
38(1):131-137,
2007.
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[MECH-06] L. Mechtouff,
M. Hermier,
B Nader,
S Cartalat,
L. Derex,
S. Cakmak,
J. Honnorat,
and N. Nighoghossian.
Stroke MRI may result in a therapeutic dilemma.
Eur Neurol,
56(4):(235),
2006.
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[NIGH-06e] N. Nighoghossian,
L. Derex,
and P. Douek.
The vulnerable carotid artery plaque : current imaging methods and new perspective.
Stroke,
36(12):2764-2772,
2006.
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[NIGH-06f] N. Nighoghossian,
M. Picot,
C. Baraza,
D Felten,
and M. Hermier.
Reversible acute postpartum cerebral angiopathy.
Rev Neurol (Paris),
162(10):(1014-8),
2006.
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[NIGH-06a] N. Nighoghossian,
L. L. Zeng,
L. Derex,
S. Cakmak,
and P. Trouillas.
Warning Compulsive Behaviour Preceding Acute Ischemic Stroke.
Eur Neurol,
56(1):340-347,
2006.
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[RHEI-06] S. Rheims,
N. Nighoghossian,
M. Hermier,
M. Formaglio,
S. Cakmak,
L. Derex,
and P. Trouillas.
Reversible acute postpartum cerebral angiopathy.
Rev Neurol (Paris),
162(10):(1014-8),
2006.
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[ROCH-05b] J.A. Roch,
N. Nighoghossian,
M. Hermier,
S. Cakmak,
M. Picot,
and J. Honnorat.
Transient neurologic symptoms related to cerebral amyloid angiopathy : usefulness of T2*-weighted imaging.
Cerebrovasc Dis,
20(5):412-414,
2006.
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[SERF-06] J. M. Serfaty,
M. Nonent,
N. Nighoghossian,
F. Rouhart,
L. Derex,
C. Rotaru,
P. Chirossel,
G. Thabut,
B. Guias,
J.F. Heautot,
P. Gouny,
A. De La Vega,
C. Pachai,
R. Ecochard,
J. Villard,
and P. Douek.
Plaque density on CT, a potential marker of ischemic stroke.
Neurology,
66(1):118-120,
2006.
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[WIAR-06b] M. Wiart,
N. Davoust,
J.B. Pialat,
V. Desestret,
S. Moucharrafie,
T.H. Cho,
M. Mutin,
J.B. Langlois,
O. Beuf,
J. Honnorat,
N. Nighoghossian,
and Y. Berthezène.
CMR 2005: MRI of cerebral ischemia with ultra-small superparamagnetic particles of iron oxide in mice.
Contrast Media Mol Imaging,
1(2):55-56,
2006.
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[ANDR-05] G. Androdias,
M. Hermier,
F. Turjman,
J. Honnorat,
and N. Nighoghossian.
Simultaneous subarachnoid hemorrhage and cerebellar infarct revealing vertebral artery aneurysm : acute MRI assessment.
Arch Neurol,
62(7):1158-1159,
2005.
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[COTT-05f] F. Cotton,
S. Kamoun,
F. Rety-Jacob,
V A. Tran-Minh,
N. Nighoghossian,
and M. Hermier.
Acute hypertensive encephalopathy with widespread small-vessel disease at MRI in a diabetic patient: pathogenetic hypotheses.
Neuroradiology,
47(8):599-603,
2005.
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[DERE-05] L. Derex,
M. Hermier,
P. Adeleine,
J.B. Pialat,
M. Wiart,
Y. Berthezène,
F. Philippeau,
J. Honnorat,
J.C. Froment,
P. Trouillas,
and N. Nighoghossian.
Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator.
J Neurol Neurosur Ps,
76:70-75,
2005.
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[HERM-05] M. Hermier,
N. Nighoghossian,
L. Derex,
M. Wiart,
C. Nemoz,
Y. Berthezène,
and J.C. Froment.
Hypointense leptomeningeal vessels at T2*-weighted MRI in acute ischemic stroke.
Neurology,
65:652-653,
2005.
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[PIAL-05] J.B. Pialat,
M. Wiart,
N. Nighoghossian,
P. Adeleine,
L. Derex,
M. Hermier,
J.C. Froment,
and Y. Berthezène.
Evolution of Lesion Volume in Acute Stroke Treated by Intravenous t-PA.
J Magn Reson Imaging,
22:23-28,
2005.
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[CAKM-04] S. Cakmak,
M. Hermier,
A. Montavont,
L. Derex,
F. Mauguière,
P. Trouillas,
and N. Nighoghossian.
T2* weighted MRI in cortical thrombosis.
Neurology,
63:1698,
2004.
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[DERE-04b] L. Derex,
M. Hermier,
P. Adeleine,
J.B. Pialat,
M. Wiart,
Y. Berthezène,
J.C. Froment,
P. Trouillas,
and N. Nighoghossian.
Influence of the site of arterial occlusion on multiple baseline hemodynamic MRI parameters and post-thrombolytic recanalization in acute stroke.
Neuroradiology,
46:883-887,
2004.
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[HONN-04] L. Derex,
N. Nighoghossian,
M. Hermier,
P. Adeleine,
Y. Berthezène,
F. Philippeau,
J. Honnorat,
J.C. Froment,
and P. Trouillas.
Influence of pre-treatment MRI parameters on clinical outcome, recanalization and infarct size in 49 stroke patients treated by intravenous tissue plasminogen activator.
J Neurol Sci,
225(1-2):3-9,
2004.
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[DERE-04c] L. Derex,
N. Nighoghossian,
M. Hermier,
P. Adeleine,
F. Philippeau,
J. Honnorat,
H. Yilmaz,
P. Dardel,
J.C. Froment,
and P. Trouillas.
Thrombolysis for ischemic stroke in patients with old microbleeds on pretreatment MRI.
Cerebrovasc Dis,
17:238-241,
2004.
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[DERE-04a] L. Derex,
N. Nighoghossian,
M. Hermier,
J.B. Pialat,
M. Wiart,
F. Philippeau,
P. Adeleine,
J. Honnorat,
J.C. Froment,
Y. Berthezène,
and P. Trouillas.
Magnetic Resonance Imaging: Significance of Early Ischemic Changes on Computed Tomography.
Cerebrovasc Dis,
18:232-235,
2004.
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[HERM-04c] M. Hermier and N. Nighoghossian.
Contribution of Susceptibility-Weighted imaging to acute stroke assessment.
Stroke,
35(8):989-1994,
2004.
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[MONT-04g] A. Montavont,
N. Nighoghossian,
L. Derex,
M. Hermier,
J. Honnorat,
F. Philippeau,
M. Belo,
F. Turjman,
P. Adeleine,
J.C. Froment,
and P. Trouillas.
Intravenous rt-PA in vertebrobasilar acute infarcts.
Neurology,
62:1854-1856,
2004.
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[NONE-04] M. Nonent,
J.M. Serfaty,
N. Nighoghossian,
L. Derex,
and P. Douek.
Concordance rate differences of three non invasive imaging techniques to measure carotid stenosis in clinical routine. Results of the CARMEDAS multicenter study.
Stroke,
pp 682-686,
2004.
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[CAKM-03] S. Cakmak,
L. Derex,
M. Berruyer,
N. Nighoghossian,
F. Philippeau,
P. Adeleine,
M. Hermier,
J.C. Froment,
and P. Trouillas.
Cerebral venous thrombosis : clinical outcome and systematic screening of prothrombotic factors.
Neurology,
60:1175-1177,
2003.
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[HERM-03b] M. Hermier,
A.S. Ibrahim,
M. Wiart,
P. Adeleine,
F. Cotton,
P. Dardel,
L. Derex,
Y. Berthezène,
N. Nighoghossian,
and J.C. Froment.
The delayed perfusion sign at MRI : a potential marquer of collateral leptomeningeal blood flow in acute stroke ?.
J Neuroradiol,
30(3):172-179,
2003.
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[HERM-03a] M. Hermier,
N. Nighoghossian,
P. Adeleine,
Y. Berthezène,
L. Derex,
H. Yilmaz,
J.F. Dugor,
P. Dardel,
F. Cotton,
F. Philippeau,
P. Trouillas,
and J.C. Froment.
Early magnetic resonance imaging prediction of arterial recanalization and late infarct volume in acute carotid artery stroke.
J Cereb Blood Flow Metab,
23(2):240-248,
2003.
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[HERM-03d] M. Hermier,
N. Nighoghossian,
L. Derex,
P. Adeleine,
M. Wiart,
Y. Berthezène,
F. Cotton,
J. B. Pialat,
P. Trouillas,
and J.C. Froment.
Hypointense transcerebral veins at T2* weighted MRI: a marquer of hemorrhagic transformation risks in patients treated by IV tissu plasminogen activator.
J Cereb Blood Flow Metab,
23(11):1362-1370,
2003.
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[HEUS-03] P.U. Heuschmann,
K. Berger,
B. Misselwitz,
P. Hermanek,
C. Leffmann,
M. Adelmann,
H.J. Buecker-Nott,
J. Rother,
B. Neundoerfer,
P.L. Kolominsky-Rabas,
and N. Nighoghossian.
Frequency of thrombolytic therapy in patients with acute ischemic stroke and the risk of in-hospital mortality: the german stroke registers study group.
Stroke,
34(5):1106-1113,
2003.
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[MONT-03g] A. Montavont,
N. Nighoghossian,
M. Hermier,
L. Derex,
F. Philippeau,
J. Honnorat,
Y. Berthezène,
J.C. Froment,
L. Caplan,
and P. Trouillas.
Hemiplegia in posterior cerebral artery occlusion : acute diffusion and perfusion MRI assessment.
Cerebrovasc Dis,
16:452-453,
2003.
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[NIGH-03a] N. Nighoghossian,
M. Hermier,
P. Adeleine,
L. Derex,
J.F. Dugor,
F. Philippeau,
H. Yilmaz,
J. Honnorat,
P. Dardel,
Y. Berthezène,
J.C. Froment,
and P. Trouillas.
Baseline magnetic resonance imaging parameters and stroke outcome in patients treated by intravenous tissue plasminogen activator.
Stroke,
34(2):458-463,
2003.
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[DERE-02a] L. Derex,
P. Adeleine,
N. Nighoghossian,
J. Honnorat,
and P. Trouillas.
Factors influencing early admission in a french stroke unit.
Stroke,
33:153-159,
2002.
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[DERE-02c] L. Derex,
N. Nighoghossian,
M. Hermier,
P. Adeleine,
J.C. Froment,
and P. Trouillas.
Early detection of cerebral arterial occlusion on magnetic resonance angiography. Predictive value of the baseline NIHSS score and impact on neurological outcome.
Cerebrovasc Dis,
13(4):225-229,
2002.
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[NIGH-02a] N. Nighoghossian,
M. Hermier,
P. Adeleine,
K. Blanc-Lasserre,
L. Derex,
J. Honnorat,
F. Philippeau,
J. F. Dugor,
J.C. Froment,
and P. Trouillas.
Old microbleeds, a potential factor of cerebral bleeding after ischemic stroke. A gradient-echo T2*-weighted brain MRI study.
Stroke,
33:735-742,
2002.
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[DERE-01a] L. Derex,
N. Nighoghossian,
M. Perinetti,
J. Honnorat,
and P. Trouillas.
Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus.
Neurology,
57:2122-2125,
2001.
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[HERM-01] M. Hermier,
N. Nighoghossian,
L. Derex,
Y. Berthezène,
K. Blanc-Lasserre,
P. Trouillas,
and J.C. Froment.
MRI of acute post-ischemic cerebral hemorrhage in stroke patient : diagnosis with T2*-weighted gradient-echo sequences.
Neuroradiology,
43:809-815,
2001.
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[NIGH-01a] N. Nighoghossian,
M. Hermier,
Y. Berthezène,
M. Wiart,
L. Derex,
J. Honnorat,
P. Trouillas,
F. Turjman,
and J.C. Froment.
Early diagnosis of hemorrhagic transformation. Diffusion/perfusion weighted MRI versus CT-Scan.
Cerebrovasc Dis,
11(3):151-156,
2001.
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[WIAR-01b] M. Wiart,
N. Rognin,
A. Baskurt,
N. Nighoghossian,
J.C. Froment,
and Y. Berthezène.
Perfusion-based segmentation of the humain brain using similarity mapping.
Magn Reson Med,
45(2):261-268,
2001.
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[BLAN-00] K. Blanc-Lasserre,
N. Nighoghossian,
L. Derex,
P. Lucain,
F. Turjman,
Y. Berthezène,
J.C. Froment,
and P. Trouillas.
Diffusion-weighted MRI in acute mutism.
Cerebrovasc Dis,
10:155-157,
2000.
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[DERE-00a] L. Derex,
N. Nighoghossian,
F. Turjman,
M. Hermier,
J. Honnorat,
P.H. Neuschwander,
and P. Trouillas.
Intravenous tPA in acute ischemic stroke related to internal carotid artery dissection.
Neurology,
(54):2159-2161,
2000.
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[TROU-00] P. Trouillas,
L. Derex,
N. Nighoghossian,
J. Honnorat,
W. Li,
P.H. Neuschwander,
G. Riche,
Y. Berthezène,
F. Turjman,
and J.C. Froment.
rtPA intravenous thrombolysis in anterior choroidal artery territory stroke.
Neurology,
(54):666-673,
2000.
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[WIAR-00a] M. Wiart,
Y. Berthezène,
P. Adeleine,
P. Feugier,
P. Trouillas,
J.C. Froment,
and N. Nighoghossian.
Vasodilatory response of border zones to Acetazolamide before and after endarterectomy : an echo planar imaging-dynamic susceptibility contrast-enhanced MRI study in patients with high-grade unilateral internal carotid artery stenosis.
Stroke,
31(7):1561-1565,
2000.
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[NIGH-99a] N. Nighoghossian,
Y. Berthezène,
P. Adeleine,
M. Wiart,
J. Damien,
L. Derex,
R. Itti,
J.C. Froment,
and P. Trouillas.
Effects of subcortical cerebrovascular lesions on cortical hemodynamic parameters assessed by perfusion magnetic resonance imaging.
Cerebrovasc Dis,
9:136-141,
1999.
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[NIGH-99b] N. Nighoghossian,
L. Derex,
F. Turjman,
J. Honnorat,
P. Lucain,
Y. Berthezène,
F. Artru,
J.C. Froment,
and P. Trouillas.
Hyperacute diffusion-weighted MRI in basilar occlusion treated with intra-arterial t-PA.
Cerebrovasc Dis,
9:351-354,
1999.
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[THOB-99] S. Thobois,
N. Nighoghossian,
J.F. Mazoyer,
J. Honnorat,
L. Derex,
J.C. Froment,
and P. Trouillas.
Thrombophlébite corticale et anomalie veineuse du développement.
Rev Neurol,
(155):48-50,
1999.
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[BERT-98b] Y. Berthezène,
N. Nighoghossian,
J. Damien,
L. Derex,
P. Trouillas,
and J.C. Froment.
Effects of thalamic hemorrhage on cortical hemodynamic parameters assessed by perfusion MR imaging.
J Neurosci,
157:67-72,
1998.
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[BERT-98a] Y. Berthezène,
N. Nighoghossian,
R. Meyer,
J. Damien,
L. Cinotti,
P. Adeleine,
P. Trouillas,
and J.C. Froment.
Can cerebrovascular reactivity by assessed by dynamic susceptibility contrast-enhanced MR imaging ?.
Neuroradiology,
40:1-5,
1998.
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[TROU-98] P. Trouillas,
N. Nighoghossian,
L. Derex,
P. Adeleine,
J. Honnorat,
P. H. Neuschwander,
G. Riche,
J.C. Getenet,
W. Li,
J.C. Froment,
F. Turjman,
D. Malicier,
G. Fournier,
A. I. Gabry,
X. Ledoux,
Y. Berthezène,
P. French,
and M. Dechavanne.
Thrombolysis with intravenous rtPA in a series of 100 cases of acute carotid territory stroke : determination of etiological, topographic, and radiological outcome factors.
Stroke,
29(12):2529-2540,
1998.
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[BERT-97a] Y. Berthezène,
N. Nighoghossian,
R. Meyer,
J. Damien,
L. Cinotti,
P. Adeleine,
P. Trouillas,
and J.C. Froment.
Course of vasomotor reactivity using dynamic susceptibility contrast-enhanced MR imaging in a patient with high grade internal carotid artery stenosis. Pre and post surgical findings.
Cerebrovasc Dis,
(7):235-238,
1997.
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[NIGH-97] N. Nighoghossian,
Y. Berthezène,
R. Meyer,
L. Cinotti,
P. Adeleine,
J.C. Froment,
and P. Trouillas.
Assessment of cerebrovascular reactivity by dynamic susceptibility contrast-enhanced MR imaging.
J Neurosci,
149(2):171-176,
1997.
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[NIGH-96] N. Nighoghossian,
Y. Berthezène,
B. Philippon,
P. Adeleine,
J.C. Froment,
and P. Trouillas.
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