Frameworks:

GIMIAS (http://gimias.org/): GIMIAS is a workflow-oriented environment for solving advanced biomedical image computing and individualized simulation problems, which is extensible through the development of problem-specific plug-ins. GIMIAS is particularly tailored to integrate tools from medical imaging, computational modeling, numerical methods and computer graphics to provide scientific developers and researchers with a software framework for building a wide variety of tools. Multi-modal image processing, personalized model creation, numerical simulation and visualization of simulation results are some of the possible applications for which GIMIAS has been designed. The aim of this framework is to combine tools from different areas of knowledge providing a framework for multi-disciplinary research and clinical study. GIMIAS allows building medical prototypes for clinical evaluation, in the areas of medical image analysis, modeling and simulation. It simplifies the integration of tools needed to build new clinical workflows, and the use of common libraries for user interfaces, visualization, image processing, DICOM access etc., that are commonly used as standard in Virtual Physiological Human (VPH) research. GIMIAS is released under a BSD License to allow cooperation between different institutes and developers. It is developed by the Center for Computational Image and Simulation Technologies in Biomedicine (CISTIB) at Universitat Pompeu Fabra, Barcelona, Spain.

medInria is a multi-platform medical image processing and visualization software, and it's free. Through an intuitive user interface, medInria offers from standard to cutting-edge processing functionalities for medical images such as 2D/3D/4D image visualization, image registration, diffusion MR processing and tractography. medInria can be used for a wide variety of tasks. It provides in its current release 6 main feature categories including: Database management and file import: DICOM read, PACS interrogation, various file formats handling, etc.; Visualization: 2D to 4D image visualization, tensor, surface visualization in a drag&drop and tabbed interface; Diffusion images processing: from tensor estimation to tractography, including the visualization of tensor fields and bundling of fibre tracts; Image segmentation: manual interactive (and soon automatic) segmentation of images; Registration of images: register images utilizing either linear or non-linear transformations; Filtering of images: Apply basic or advanced filters to an image (from some ITK-based basic filters to more advanced denoising algorithms). medInria is developed by Inria, the French Research Institute in Mathematics and Informatics, and available online (http://med.inria.fr).

Creatools (http://www.creatis.insa-lyon.fr/site/en/CreaTools_home) are a collection of medical image processing, visualization and interaction utilities and development tools. These tools are built on top of BBTK (black-box toolkit), a flexible framework for designing, programming, testing and prototyping of applications. BBTK provides the user with libraries of high-level components to construct graphical interfaces including input/output (file management), display, interaction, data processing, etc. Currently, these components (black boxes) are mainly based on the following third-party libraries: VTK, ITK, wxWidgets and Qt. Developers can use the existing black boxes and/or create new ones, and assemble them into pipelines, in order to realize either stand-alone applications or new complex black boxes (meta-widgets), reusable in other applications. More than 300 black boxes are currently available. Pipeline editing and testing are made easy by a user-friendly graphical editor providing several forms of on-line help. CreaTools are cross-platform and have been developed in C++. Designed at CREATIS, they evolve with contributions from Colombian Universities: los Andes and Javeriana.