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    Hello, Bilal,<br>
    <br>
    I'd have to verify this (maybe Vivien can also comment on that), but
    I think the dir-lab data are not in HU, i.e., the grey values are
    all positive, from 0 to 4096. The algorithms in clitkExtractLung
    apply some thresholding operations that depend on a data set in HU,
    roughly from -1024 to 3072. <br>
    <br>
    To cope with it, you can either play with the parameters
    seedPreProcessingThreshold and upperThresholdForTrachea in
    clitkExtratLung (depending on TYPE)<br>
    "upperThresholdForTrachea"    -    "0: Initial upper threshold for
    trachea"  default="-900"<br>
    "seedPreProcessingThreshold"   -  "1: Threshold for the
    pre-processing step of the algorithm" default="-400"<br>
    <br>
    or, to be on the safe side, shift your grey values prior to
    launching clitkExtractLung. You can do it by creating an image with
    -1024 everywhere (clitkCreateImage does the job) and then applying
    the shift by adding the two images with clitkImageArithm. <br>
    <br>
    In any case, using --verboseRG might also give some extra insights.<br>
    <br>
    I hope this helps!<br>
    <br>
    Best,<br>
    Rômulo<br>
    <br>
    <div class="moz-cite-prefix">On 23/10/2013 14:15, Bilal Tahir wrote:<br>
    </div>
    <blockquote
cite="mid:CAFZ9P6Fsx-YP2zYzC7WNXkJeKaGGCjqYNYiusCwcWAcCwjbq0g@mail.gmail.com"
      type="cite">
      <div dir="ltr">Thanks Vivien,
        <div><br>
        </div>
        <div>I've got passed the .afdb stage. However I'm getting errors
          at the 'search for trachea' stage for both the original and
          LOLA11 algorithms. The dataset is the inspiration scans for
          patient 1 of the dir-lab copd data. </div>
        <div><br>
        </div>
        <div><span style="background-color:rgb(255,0,0)">1) LOLA 11:</span></div>
        <div><span style="background-color:rgb(255,0,0)"><br>
          </span></div>
        <div>
          <div><span style="background-color:rgb(255,0,0)">[md1bat@testnode02
              mhd]$ clitkExtractLung --verboseStep 1 -i copd1_00.mhd -a
              default.afdb -o 00_lungs.mhd --type=1</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 1 --
              Copy and crop input image to 'patient' extends</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 2 -- Set
              background to initial image</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 3 --
              Remove Air</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 4 --
              Search for the trachea</span></div>
          <div><span style="background-color:rgb(255,0,0)"><br>
            </span></div>
          <div><span style="background-color:rgb(255,0,0)">itk::InvalidRequestedRegionError
              (0x2bca660)</span></div>
          <div><span style="background-color:rgb(255,0,0)">Location:
              "unknown" </span></div>
          <div><span style="background-color:rgb(255,0,0)">File:
              /home/md1bat/Source/itk/Modules/Core/Common/src/itkDataObject.cxx</span></div>
          <div><span style="background-color:rgb(255,0,0)">Line: 411</span></div>
          <div><span style="background-color:rgb(255,0,0)">Description:
              Requested region is (at least partially) outside the
              largest possible region.</span></div>
        </div>
        <div><span style="background-color:rgb(255,0,0)"><br>
          </span></div>
        <div><span style="background-color:rgb(255,0,0)">2) Original
            (type=0)</span></div>
        <div><span style="background-color:rgb(255,0,0)"><br>
          </span></div>
        <div>
          <div><span style="background-color:rgb(255,0,0)">[md1bat@testnode02
              mhd]$ clitkExtractLung --verboseStep 1 -i copd1_00.mhd -a
              default.afdb -o 00_lungs.mhd --type=0</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 1 --
              Copy and crop input image to 'patient' extends</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 2 -- Set
              background to initial image</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 3 --
              Remove Air</span></div>
          <div><span style="background-color:rgb(255,0,0)">Step 4 --
              Search for the trachea</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.53 cc) seems not correct. I
              skip some slices (0) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4037.01 cc) seems not correct. I
              skip some slices (5) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4036.86 cc) seems not correct. I
              skip some slices (10) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4036.39 cc) seems not correct. I
              skip some slices (15) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4036.07 cc) seems not correct. I
              skip some slices (20) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.31 cc) seems not correct. I
              skip some slices (25) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.54 cc) seems not correct. I
              skip some slices (30) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.49 cc) seems not correct. I
              skip some slices (35) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.39 cc) seems not correct. I
              skip some slices (40) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.57 cc) seems not correct. I
              skip some slices (45) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4035.69 cc) seems not correct. I
              skip some slices (50) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4036.09 cc) seems not correct. I
              skip some slices (55) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">         The
              volume of the trachea (4036.34 cc) seems not correct. I
              skip some slices (60) and restart to find seeds.</span></div>
          <div><span style="background-color:rgb(255,0,0)">2 : Number of
              slices to skip to find trachea too high = 65</span></div>
          <div><span style="background-color:rgb(255,0,0)"><br>
            </span></div>
          <div><span style="background-color:rgb(255,0,0)">itk::ExceptionObject
              (0x377f970)</span></div>
          <div><span style="background-color:rgb(255,0,0)">Location:
              "Unknown" </span></div>
          <div><span style="background-color:rgb(255,0,0)">File:
              /home/md1bat/Source/vv/segmentation/clitkExtractLungFilter.txx</span></div>
          <div><span style="background-color:rgb(255,0,0)">Line: 266</span></div>
          <div><span style="background-color:rgb(255,0,0)">Description:
              No seeds for trachea... Aborting.</span></div>
        </div>
        <div><span style="background-color:rgb(255,0,0)"><br>
          </span></div>
        <div><span style="background-color:rgb(255,0,0)">3) Manually
            setting a higher number of slices than 65</span></div>
        <div><span style="background-color:rgb(255,0,0)"><br>
          </span></div>
        <div>
          <div><span style="background-color:rgb(255,0,0)">[md1bat@testnode02
              mhd]$ clitkExtractLung --verbose 1 -i copd1_00.mhd -a
              default.afdb -o 00_lungs.mhd --skipslices=90</span></div>
          <div><span style="background-color:rgb(255,0,0)">Input is 3D
              short.</span></div>
          <div><span style="background-color:rgb(255,0,0)">Reading
              [copd1_00.mhd] ... </span></div>
          <div><span style="background-color:rgb(255,0,0)">2 : Number of
              slices to skip to find trachea too high = 95</span></div>
          <div><span style="background-color:rgb(255,0,0)"><br>
            </span></div>
          <div><span style="background-color:rgb(255,0,0)">itk::ExceptionObject
              (0x3a379d0)</span></div>
          <div><span style="background-color:rgb(255,0,0)">Location:
              "Unknown" </span></div>
          <div><span style="background-color:rgb(255,0,0)">File:
              /home/md1bat/Source/vv/segmentation/clitkExtractLungFilter.txx</span></div>
          <div><span style="background-color:rgb(255,0,0)">Line: 266</span></div>
          <div><span style="background-color:rgb(255,0,0)">Description:
              No seeds for trachea... Aborting.</span></div>
        </div>
        <div><br>
        </div>
        <div>As you can see, I keep failing at the search trachea stage
          even by trying various different options for slices to skip
          for the trachea. Please let me know if you have any
          suggestions that can help.</div>
        <div><br>
        </div>
        <div>Best wishes,</div>
        <div><br>
        </div>
        <div>Bilal</div>
        <div class="gmail_extra"><br>
          <br>
          <div class="gmail_quote">On 23 October 2013 16:51, Vivien
            Delmon <span dir="ltr"><<a moz-do-not-send="true"
                href="mailto:vivien.delmon@creatis.insa-lyon.fr"
                target="_blank">vivien.delmon@creatis.insa-lyon.fr</a>></span>
            wrote:<br>
            <blockquote class="gmail_quote" style="margin:0 0 0
              .8ex;border-left:1px #ccc solid;padding-left:1ex">On
              10/18/2013 12:08 AM, Bilal Tahir wrote:<br>
              <blockquote class="gmail_quote" style="margin:0 0 0
                .8ex;border-left:1px #ccc solid;padding-left:1ex">
                Dear VV community,<br>
                <br>
                ...
                <div class="im"><br>
                  <br>
                  Also I would like to know if the LOLA11 paper below is
                  the correct<br>
                  reference if I decide to use your method for
                  publications?<br>
                  <br>
                  <a moz-do-not-send="true"
href="http://lola11.com/Results/displayApproved?result=20110708160218_86_CREATIS_CLB_Lyon_graphcut&file=20110708160218_86_CREATIS_CLB_Lyon_graphcut_lola11.pdf"
                    target="_blank">http://lola11.com/Results/displayApproved?result=20110708160218_86_CREATIS_CLB_Lyon_graphcut&file=20110708160218_86_CREATIS_CLB_Lyon_graphcut_lola11.pdf</a><br>
                </div>
              </blockquote>
              <br>
              Part of the work presented in this paper have been
              implemented in clitkExtractLung but you need to explicitly
              ask the tool to use it :<br>
              <br>
              Step 2 : find trachea:<br>
                --type=INT trachea finding algorithm (0: original;
              1:LOLA11) (default=`0')<br>
              <br>
              The second part about graphcut labeling were not included
              in this tool since we never really need to separate lungs.<br>
              <br>
              Last time I tried to activate --type=1 it failed, I will
              have a look at it one day.<br>
              <br>
              As far as I know there is no other paper that describe
              what we have implemented in this tool, so this paper
              should be the one to cite.<span class="HOEnZb"><font
                  color="#888888"><br>
                  <br>
                  -- <br>
                  Vivien Delmon<br>
                  PhD student at CREATIS, Lyon<br>
                  Supported by ANRT and ELEKTA<br>
                  <a moz-do-not-send="true"
                    href="http://www.creatis.insa-lyon.fr/rio"
                    target="_blank">http://www.creatis.insa-lyon.fr/rio</a></font></span>
              <div class="HOEnZb">
                <div class="h5"><br>
                  _______________________________________________<br>
                  vv mailing list<br>
                  <a moz-do-not-send="true"
                    href="mailto:vv@creatis.insa-lyon.fr"
                    target="_blank">vv@creatis.insa-lyon.fr</a><br>
                  <a moz-do-not-send="true"
                    href="http://www.creatis.insa-lyon.fr/mailman/listinfo/vv"
                    target="_blank">http://www.creatis.insa-lyon.fr/mailman/listinfo/vv</a><br>
                </div>
              </div>
            </blockquote>
          </div>
          <br>
          <br clear="all">
          <div><br>
          </div>
          -- <br>
          <div dir="ltr">Bilal Tahir,
            <div>James Morrison Researcher in Radiotherapy Imaging,</div>
            <div>Department of Clinical Oncology,</div>
            <div>University of Sheffield</div>
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